Thrombolytics Agents
Thrombolytics
The Competitive Intelligence Report Thrombolytics as of April 2007 provides a competitor analysis in the development pipeline of novel projects acting as 4 th generation plasminogen activators or as directly acting fibrinolytics such as plasmin and includes variants and engineered proteins. Thrombolytics are established treatments of acute myocardial infarction and also used in stroke and for catheter clearance. Novel thrombolytics are being evaluated for acute peripheral arterial occlusive disease, visual disorders such as vitreolysis and diabetic retinopathy, and neuroprotection in acute ischemic stroke and deep vein thrombosis. Numerous companies in “off-patent” countries have developed recombinant and biosimilar thrombolytics and introduced them into the market.
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